Mounjaro vs Wegovy UK
A detailed comparison of the two leading weight loss injections in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Active Ingredient | Tirzepatide | Semaglutide |
| Mechanism | Dual Agonist (GLP-1 + GIP) | GLP-1 Agonist |
| Avg Weight Loss | Up to 22.5% | Up to 15% |
| Frequency | Weekly Injection | Weekly Injection |
| Starting Price | ~£149 | ~£169 |
| Maintenance Dose | 5mg, 10mg or 15mg | 2.4mg |
| Needles Included | No (Usually separate) | Yes (Built-in) |
Mechanism of Action
Mounjaro
Mounjaro is the first "dual agonist" medication. It mimics two hormones: GLP-1 and GIP. This dual action is believed to be the reason for its superior weight loss results in clinical trials.
Wegovy
Wegovy mimics a single hormone: GLP-1. It has been used for longer and has a well-established safety profile. It is highly effective, though slightly less so than Mounjaro on average.
Effectiveness
In a head-to-head clinical trial (SURMOUNT-1 vs STEP trials comparison), Mounjaro demonstrated greater weight loss than Wegovy. Patients on the highest dose of Mounjaro lost an average of 22.5% of their body weight, compared to around 15% for Wegovy.
However, both medications are significantly more effective than diet and exercise alone, or older weight loss medications like Saxenda.
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22.5%
Mounjaro Avg.
15%
Wegovy Avg.
Cost Comparison
Currently in the UK, Mounjaro is often slightly cheaper than Wegovy, with starting prices around £149 compared to £169-£199 for Wegovy. However, prices vary by pharmacy and dose.
Don't Overpay for Your Prescription
Prices vary significantly between pharmacies. By comparing providers, you can save up to £1,200 per year on your treatment journey.
Verdict: Which should you choose?
Mounjaro appears to be the more effective option for weight loss and is currently slightly more affordable. It is a good choice if you want the maximum possible weight loss.
Wegovy is a great alternative if Mounjaro is not suitable for you or if you prefer a medication with a longer track record. Both are excellent choices for weight management.
Ready to Compare UK Prices?
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