Safety Information

Wegovy Side Effects Explained

Wegovy (Semaglutide) is a powerful weight loss medication, but it can cause side effects. Here is everything you need to know about managing them safely.

Like all GLP-1 agonists, Wegovy affects your digestive system to help you lose weight. This mechanism means that gastrointestinal side effects are very common, especially when you first start taking the medication or increase your dose.

Good News: For most people, side effects are mild and tend to go away after a few weeks as your body gets used to the medicine.

Most Common Side Effects

These affect more than 1 in 10 users:

Nausea

Feeling sick is the #1 reported side effect.

Remedy: Ginger tea or peppermint.

Fatigue

Feeling unusually tired or weak.

Remedy: Ensure you are eating enough calories.

Headache

Often caused by dehydration.

Remedy: Drink water consistently.

Digestive Issues

Diarrhoea, constipation, or gas.

Remedy: Over-the-counter remedies usually help.

Other Potential Effects

  • Dizziness
  • Stomach pain
  • Bloating
  • Belching (Burping)
  • Gas (Flatulence)
  • Inflamed stomach (Gastritis)
  • Acid reflux
  • Hair loss (rare, usually temporary)

Serious Warnings

While rare, serious complications can occur. Seek immediate medical help if you notice:

Pancreatitis Symptoms

Severe, persistent pain in your abdomen that may reach to your back, often with vomiting.

Kidney Problems

Changes in how much or how often you urinate, or swelling in your feet/ankles.

Vision Changes

Especially for patients with type 2 diabetes (diabetic retinopathy).

Low Blood Sugar (Hypoglycemia)

Dizziness, blurred vision, anxiety, irritability, mood changes, sweating, slurred speech.

Tips to Minimize Nausea

  • Eat bland, low-fat foods (crackers, toast, rice).
  • Eat smaller meals more frequently.
  • Stop eating as soon as you feel full.
  • Avoid lying down after meals.
  • Go outside for fresh air.

Wegovy Resources

Need Medical Advice?

Always read the Patient Information Leaflet (PIL) included with your medication.

View Official Leaflet

Ready to Compare UK Prices?

Find the best deals on Mounjaro, Wegovy, and Saxenda from GPhC-registered pharmacies.